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A tumor’s ‘signature’ reveals the key to treatment in precision oncology

A potential response to cancer is written — on a microscopic level — in its very tumor cells. For decades, treatment and prognosis of the disease has been largely determined by the organ, the anatomical location in which the cancerous mass is located. But now, science has placed a spotlight on something more ambitious: learning the tumor’s signature, or rather, the molecular alterations that characterize its malignant cells. The latest meeting of the American Society of Clinical Oncology (ASCO), which took place last weekend in Chicago, has given further impetus to precision oncology and highlighted how cancer biology, those microscopic genetic characteristics that define it, are playing an increasingly important role in determining therapeutic approach, and even predicting prognosis.

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© Lukas Kabon (Anadolu Agency / Getty)

A researcher handles samples in a laboratory in the Czech Republic.
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Longevity researcher Juan Carlos Izpisua presents latest data on aging process: ‘It is a loss of identity at the cellular level’

Scientist Juan Carlos Izpisua at the Royal National Academy of Medicine in Spain.

“If no one asks me, I know what time is. When they ask me, I no longer know,” wrote the philosopher Augustine of Hippo 17 centuries ago. Something very similar happens now with aging: we all understand what it is, but when we ask ourselves why we must age and die, doubts arise. Even the world’s leading experts face the same uncertainty: at best they offer very different answers.

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Juan Carlos Izpisua at the Royal Academy of Medicine in Madrid.
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Winette Van der Graaf, oncologist: ‘I never would have imagined seeing patients with colorectal cancer at age 19′

Winette Van der Graaf, oncologist and president of the European Organisation for Research and Treatment of Cancer, photographed in Barcelona.

A glance at Winette Van der Graaf’s extensive résumé is enough to certify that this Dutch oncologist has been an exceptional witness, if not a fundamental part, of the great scientific revolution that cancer research has undergone in recent decades. An expert in sarcomas and cancers in teens and young adults, Van der Graaf was one of the pioneers in providing care — and personalized assistance — to people between the ages of 15 and 39 who develop cancer. Sometimes in no man’s land, halfway between pediatric and adult oncology, cancer at this age puts life “on hold,” says Van der Graaf.

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Over HK$140k raised for late Hong Kong hairstylist Pitt Cheung to be donated to cancer NGO

Pitt Cheung

Funds raised for a Hong Kong hairstylist who died from nasopharyngeal cancer in April will be donated to NGO Cancer Information, as per his wishes.

Pitt Cheung
Pitt Cheung. Photo: gogetfunding.com.

Two rounds of fundraising initiatives for Pitt Cheung raised a total of HK$831,000 for his specialist treatment, leaving a balance of over HK$140,000 after his passing in April.

The fundraiser said that Cheung had exhausted radiotherapy, chemotherapy and immunotherapy treatments at public hospitals, so he switched to a recommended chemotherapy drug called Nab-paclitaxel, costing HK$72,000 per month.

Cheung died peacefully in hospital on April 26. A funeral for the 44-year-old was held on May 9.

A post on Pitt Cheung's fundraising Instagram profile on June 7, 2026.
A post on Pitt Cheung’s fundraising Instagram profile on June 7, 2026. Photo: @crowdfunding_for_pitt, via Instagram.

“After deduct[ing] the expenses for chemotherapy, follow-up appointments, check-ups, the chemo port surgery and hospitalisation, we are left with HK$140,620. Per Pitt’s wishes, we will donate this sum to NGO @cancer_information,” a post on Cheung’s fundraising Instagram account said on Sunday.

“This NGO provided lots of professional support and companionship to Pitt when he was fighting cancer, and we hope the funds can be used to help more people.”

The post thanked the Hong Kong United Oncology Centre, where he was cared for, as well as donors, friends and family who supported his journey.

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